Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 134
interventional 96
Observational 35
Registry 3

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug 17
Device 8
Other 7
Procedure 7
Drug|Procedure|Radiation 6
Behavioral 5
Drug|Procedure 5
Drug|Radiation 4
Device|Other 3
Drug|Other 3
Drug|placebo 3
Other|Procedure 3
Biological|Drug 2
Biological|Drug|Other 2
Combination Product 2
Device|Drug|Procedure 2
Drug|Other|placebo 2
Radiation 2
Behavioral|Device|Procedure 1
Behavioral|Other 1
Biological 1
Biological|Other 1
Biological|Other|Radiation 1
Biological|Radiation 1
Device|Drug 1
Diagnostic Test 1
Dietary Supplement 1
Dietary Supplement|Other 1
Drug|Other|Radiation 1
Other|placebo 1
Procedure|Radiation 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 45
China 9
France 7
India 6
Taiwan 6
Canada 4
Brazil 2
Egypt 2
NA 2
Netherlands 2
United Kingdom 2
United States|Canada 2
Denmark 1
Germany 1
Israel 1
Italy 1
Japan 1
Norway 1
United States|Puerto Rico|South Africa 1

Sites per Study

Site_count Study_Count
1 71
2 5
3 3
4 5
5 1
6 2
7 2
8 2
10 1
35 1
228 1
508 1
789 1

Phase

Phase Study_Count
N/A 34
Phase 2 21
Phase 1/Phase 2 12
Phase 1 10
Phase 3 7
Early Phase 1 5
Phase 4 4
Phase 2/Phase 3 3

Number of Arms

Number_of_Arms Count_of_Studies
1 41
2 37
3 5
4 4
5 2
8 1
NA 6

Enrollment Metrics by Phase

Measure Early.Phase.1 N.A Phase.1 Phase.1.Phase.2 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 8.0 10.0000 3.0 13.00 14.00000 120.0000 62.0000 25.00
1st Qu. 10.0 40.0000 17.0 24.00 33.00000 181.5000 203.5000 28.75
Median 15.0 67.5000 28.0 39.00 64.00000 243.0000 310.0000 150.00
Mean 69.2 158.3235 29.1 43.00 80.90476 295.3333 573.5714 187.50
3rd Qu. 38.0 200.0000 39.0 58.75 101.00000 383.0000 621.5000 308.75
Max. 275.0 1200.0000 57.0 82.00 325.00000 523.0000 1993.0000 425.00

Trial Group Type

group_type Group_Count
Experimental 110
Active Comparator 22
Other 15
Placebo Comparator 10
No Intervention 7
NA 6

Intervention Model

intervention_model Study_Count
Parallel Assignment 46
Single Group Assignment 45
Sequential Assignment 3
Crossover Assignment 1
Factorial Assignment 1

Primary Purpose

primary_purpose Study_Count
Treatment 53
Prevention 15
Diagnostic 12
Supportive Care 6
Health Services Research 4
Screening 3
Basic Science 1
Other 1
NA 1

Observational Studies

Studies by Country

Country Study_Count
United States 18
Taiwan 6
Egypt 2
NA 2
United Kingdom 2
Belgium 1
Brazil 1
Costa Rica 1
France 1
United States|Colombia|Costa Rica 1

Sites per Study

Site_count Study_Count
1 31
3 1
5 1
6 1
14 1

Enrollment Metrics

Measure Observational
Min 10.0000
1st Qu 45.0000
Median 62.5000
Mean 375.0882
3rd Qu 100.0000
Max 8670.0000

Observation Model

observational_model Study_Count
Cohort 16
Case-Control 7
Case-Only 4
Case Control 3
Other 3
Natural History 1
NA 1

Time Perspective

time_perspective Study_Count
Prospective 25
Cross-Sectional 3
Retrospective 3
Other 2
Cross-Sectional, Retrospective/Prospective 1
Longitudinal, Prospective 1

Registries

Studies by Country

Country Study_Count
Canada 1
Sweden 1
United States 1

Sites per Study

Site_count Study_Count
1 1
2 1
75 1

Enrollment Metrics

Measure Registries
Min 100.0
1st Qu 230.0
Median 360.0
Mean 333486.3
3rd Qu 500179.5
Max 999999.0

Registry Model

observational_model Study_Count
Cohort 2
Other 1

Time Perspective

time_perspective Study_Count
Prospective 3

Follow-up

target_duration Study_Count
1 Year 1
10 Years 1
80 Years 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT00588770 Chemotherapy With or Without Bevacizumab in Treating Patients With Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT00588770 Active, not recruiting National Cancer Institute (NCI) 2018-06-05
NCT03383094 Chemoradiation vs Immunotherapy and Radiation for Head and Neck Cancer https://ClinicalTrials.gov/show/NCT03383094 Recruiting University of California, San Diego 2021-04-30
NCT02285530 GDF15 Based TPF Induction Chemotherapy for OSCC Patients https://ClinicalTrials.gov/show/NCT02285530 Recruiting Shanghai Jiao Tong University School of Medicine 2022-12-31
NCT03420963 Ex-Vivo Expanded Allogeneic NK Cells For The Treatment Of Pediatric Solid Tumors https://ClinicalTrials.gov/show/NCT03420963 Recruiting M.D. Anderson Cancer Center 2022-12-01
NCT03267914 Impact of Compliance With Fluoride Use on Caries Incidence After Cancer Therapy https://ClinicalTrials.gov/show/NCT03267914 Recruiting A.T. Still University of Health Sciences 2020-02-28
NCT03212079 Physical Activities by Technology Help (PATH) https://ClinicalTrials.gov/show/NCT03212079 Completed Johns Hopkins University 2018-03-15
NCT03096808 Adaptive Radiotherapy for Head and Neck Cancer https://ClinicalTrials.gov/show/NCT03096808 Active, not recruiting Memorial Sloan Kettering Cancer Center 2021-03-15
NCT03082534 Pembrolizumab Combined With Cetuximab for Treatment of Recurrent/Metastatic Head & Neck Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT03082534 Recruiting University of California, San Diego 2019-12-30
NCT03067610 Involved Field Elective Volume De-Intensification Radiation Therapy for Head and Neck Cancer https://ClinicalTrials.gov/show/NCT03067610 Active, not recruiting University of Texas Southwestern Medical Center 2021-12-29
NCT03017053 The Optimal Neck Treatments Strategy of Early Oral Cancer Based on Adverse Pathological Factor https://ClinicalTrials.gov/show/NCT03017053 Recruiting Shanghai Ninth People’s Hospital Affiliated to Shanghai Jiao Tong University 2025-07-31
NCT03010813 A Novel Robotic System for Single Port and Natural Orifice Transluminal Endoscopic Surgery https://ClinicalTrials.gov/show/NCT03010813 Completed Chinese University of Hong Kong 2017-10-31
NCT02981862 CaptHPV : Validation of the Method “CaptHPV” for the Diagnosis of Human Papillomavirus Associated Infiltrating Carcinomas https://ClinicalTrials.gov/show/NCT02981862 Completed Institut de Cancérologie de Lorraine 2018-06-12
NCT02946671 Study of Pre-operative Combination Therapy With Mogamulizumab and Nivolumab Against Solid Cancer Patients https://ClinicalTrials.gov/show/NCT02946671 Completed Osaka University 2020-03-31
NCT02921724 Participatory Research for Fine-tuning of a 2.0 System to Optimise Home Management of Oral Cancer Therapies. https://ClinicalTrials.gov/show/NCT02921724 Active, not recruiting Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori 2020-05-31
NCT02823847 Non Invasive Oral Cancer Screening Among HIV Infected Individuals https://ClinicalTrials.gov/show/NCT02823847 Active, not recruiting M.D. Anderson Cancer Center 2020-07-31
NCT02734537 Radiation Therapy With or Without Cisplatin in Treating Patients With Stage III-IVA Squamous Cell Carcinoma of the Head and Neck Who Have Undergone Surgery https://ClinicalTrials.gov/show/NCT02734537 Recruiting Eastern Cooperative Oncology Group 2022-05-01
NCT02608879 Oral Care Protocol for the Management of Chemotherapy and Radiation Therapy-Induced Oral Mucositis https://ClinicalTrials.gov/show/NCT02608879 Completed NYU Langone Health 2015-09-30
NCT02604121 Cytological Screening for Early Diagnosis of Precancerous or Cancerous Lesions of Oral Cavity https://ClinicalTrials.gov/show/NCT02604121 Completed University Hospital, Toulouse 2019-02-28
NCT02586207 Pembrolizumab in Combination With CRT for LA-SCCHN https://ClinicalTrials.gov/show/NCT02586207 Active, not recruiting Sanford Health 2020-06-30
NCT02584270 Prosthesis Guided Speech Rehabilitation of T1/T2 Cancers of the Tongue https://ClinicalTrials.gov/show/NCT02584270 Recruiting University of Michigan 2022-01-31
NCT03021993 Trial of Nivolumab as a Novel Neoadjuvant Pre-Surgical Therapy for Locally Advanced Oral Cavity Cancer https://ClinicalTrials.gov/show/NCT03021993 Recruiting Medical University of South Carolina 2020-12-31
NCT02478138 Sentinel Lymph Node Mapping of Oral Cancer Using Near-Infrared Fluorescence Imaging https://ClinicalTrials.gov/show/NCT02478138 Recruiting University Health Network, Toronto 2020-12-31
NCT02412241 Establishing Lymphedema and Fibrosis Measures in Oral Cancer Patients https://ClinicalTrials.gov/show/NCT02412241 Active, not recruiting Vanderbilt-Ingram Cancer Center 2020-02-29
NCT02290145 Cyclin D1 Based TPF Induction Chemotherapy for Oral Squamous Cell Carcinoma Patients at Clinical N2 Stage https://ClinicalTrials.gov/show/NCT02290145 Recruiting Shanghai Jiao Tong University School of Medicine 2023-07-31
NCT02285543 A Phase II Trial of TPF Induction Chemotherapy in cN2 OSCC Patients https://ClinicalTrials.gov/show/NCT02285543 Recruiting Shanghai Jiao Tong University School of Medicine 2023-12-31
NCT03385720 Submandibular Gland Preservation in Neck Dissection https://ClinicalTrials.gov/show/NCT03385720 Recruiting Peking University 2020-12-31
NCT02043184 Improving Adherence to Oral Cancer Agents and Self Care of Symptoms Using an IVR https://ClinicalTrials.gov/show/NCT02043184 Completed Michigan State University 2016-07-31
NCT03174275 Carboplatin, Nab-Paclitaxel, Durvalumab Before Surgery and Adjuvant Therapy in Head and Neck Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT03174275 Recruiting UNC Lineberger Comprehensive Cancer Center 2021-09-01
NCT03258554 Radiation Therapy With Durvalumab or Cetuximab in Treating Patients With Locoregionally Advanced Head and Neck Cancer Who Cannot Take Cisplatin https://ClinicalTrials.gov/show/NCT03258554 Recruiting National Cancer Institute (NCI) 2025-12-31
NCT01958762 Screening for Cancers in the Oral CAvity https://ClinicalTrials.gov/show/NCT01958762 Recruiting Centre Hospitalier Universitaire, Amiens 2018-12-31
NCT01816841 Direct Visual Fluorescence in Finding Oral Cancer in High-Risk Patients and Patients Undergoing Routine Dental Care https://ClinicalTrials.gov/show/NCT01816841 Completed Ohio State University Comprehensive Cancer Center 2016-10-03
NCT01806675 18F-FPPRGD2 PET/CT or PET/MRI in Predicting Early Response in Patients With Cancer Receiving Anti-Angiogenesis Therapy https://ClinicalTrials.gov/show/NCT01806675 Completed Stanford University 2016-12-07
NCT01790204 A Study of the Effects of PEITC on Oral Cells With Mutant p53 https://ClinicalTrials.gov/show/NCT01790204 Completed Georgetown University 2014-04-30
NCT01733797 Trismus Trial of Therabite vs Wooden Spatula in Head and Neck Cancer Patients https://ClinicalTrials.gov/show/NCT01733797 Completed The Christie NHS Foundation Trust 2015-08-31
NCT01695122 Valproic Acid and Platinum-based Chemoradiation in Locally Advanced Head and Neck Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT01695122 Completed Instituto do Cancer do Estado de São Paulo 2014-11-30
NCT01649349 The Feasibility Study of Dual-Section Nasogastric Tube https://ClinicalTrials.gov/show/NCT01649349 Completed Changhua Christian Hospital 2012-06-30
NCT01604759 Polarized Reflectance Spectroscopy for Oral Lesions https://ClinicalTrials.gov/show/NCT01604759 Completed British Columbia Cancer Agency 2015-12-31
NCT01553851 GSK1120212 in Surgically Resectable Oral Cavity Squamous Cell Cancer https://ClinicalTrials.gov/show/NCT01553851 Completed Washington University School of Medicine 2015-06-30
NCT01514552 The Use of Functional Confections in Promoting Oral Health https://ClinicalTrials.gov/show/NCT01514552 Active, not recruiting Ohio State University 2020-12-31
NCT01504932 Freeze-Dried Black Raspberries in Preventing Oral Cancer Recurrence in High At-Risk Appalachian Patients Oral Cancer Survivors https://ClinicalTrials.gov/show/NCT01504932 Completed Ohio State University Comprehensive Cancer Center 2015-04-22
NCT01473784 Transoral Robotic Surgery in Treating Patients With Benign or Malignant Tumors of the Head and Neck https://ClinicalTrials.gov/show/NCT01473784 Recruiting Ohio State University Comprehensive Cancer Center 2020-12-31
NCT01469429 Phase 1b Food Based Modulation of Biomarkers in Human Tissues at High-Risk for Oral Cancer. https://ClinicalTrials.gov/show/NCT01469429 Completed Ohio State University Comprehensive Cancer Center 2014-09-17
NCT01445405 Radiation Therapy and Bortezomib and Cetuximab With or Without Cisplatin to Treat Head and Neck Cancer https://ClinicalTrials.gov/show/NCT01445405 Completed National Institutes of Health Clinical Center (CC) 2010-08-27
NCT01440270 Neo-adjuvant Erbitux-based Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer https://ClinicalTrials.gov/show/NCT01440270 Completed Shanghai Jiao Tong University School of Medicine 2014-10-31
NCT01434394 Neoadjuvant Erbitux Based Chemotherapy for Locally Advanced Oral/Oropharyngeal Cancer https://ClinicalTrials.gov/show/NCT01434394 Completed Shanghai Jiao Tong University School of Medicine 2014-10-31
NCT01424358 Web-based Education on Oral Cancer for Primary Care Physicians in Ohio https://ClinicalTrials.gov/show/NCT01424358 Completed Creighton University 2013-09-30
NCT01418118 Assessment of the Effects of Pressors on Graft Blood Flow After Free Tissue Transfer Surgery https://ClinicalTrials.gov/show/NCT01418118 Completed Oxford University Hospitals NHS Trust 2010-02-28
NCT01365169 Post-op Wellness Program for Pancreatic Cancer Patients That Uses Patient Feedback and Real-time Provider Monitoring https://ClinicalTrials.gov/show/NCT01365169 Recruiting M.D. Anderson Cancer Center 2025-02-25
NCT01351532 Behavior Change on Oral Cancer Patients After a Localized Behavior Change Model Intervention https://ClinicalTrials.gov/show/NCT01351532 Completed China Medical University Hospital 2011-10-31
NCT04330781 Radiotherapy of Head and Neck Cancer Using an Intraoral Stent https://ClinicalTrials.gov/show/NCT04330781 Recruiting Oslo University Hospital 2022-12-31
NCT04265430 Serial Magnetic Resonance Imaging for the Prediction of Radiation-Induced Changes in Normal Tissue of Patients With Oral Cavity or Skull Base Tumors https://ClinicalTrials.gov/show/NCT04265430 Recruiting M.D. Anderson Cancer Center 2021-09-30
NCT04214912 Personalized Survivor Care Plan for Oral Cancer Patients-Effects on Physical-Psychological Functions and Return-to-Work https://ClinicalTrials.gov/show/NCT04214912 Recruiting National Taiwan University Hospital 2020-07-31
NCT04126226 Quality of Life in Patients Treated for Tongue and/or Jaw Neoplasia Before and After Speech Therapy https://ClinicalTrials.gov/show/NCT04126226 Completed Hospital de Clinicas de Porto Alegre 2019-07-31
NCT04049968 Using an APP in Post Oral Cancer Surgery to Affect Patients’ Needs and Quality of Life. https://ClinicalTrials.gov/show/NCT04049968 Completed Far Eastern Memorial Hospital 2017-12-31
NCT03993353 Tadalafil and Pembrolizumab in Recurrent or Metastatic Head and Neck Cancer https://ClinicalTrials.gov/show/NCT03993353 Recruiting University of California, San Diego 2022-12-31
NCT03934294 Acupuncture Effect on Digestion in Critically Ill Post-Operative Oral and Hypo-pharyngeal Cancer Patients https://ClinicalTrials.gov/show/NCT03934294 Recruiting China Medical University Hospital 2021-05-25
NCT03923998 Adjuvant ChemoRadiotherapy Prior to Surgery in Stage IVa Oral Cancers https://ClinicalTrials.gov/show/NCT03923998 Completed Indrayani Hospital and Cancer Institute 2019-03-15
NCT03923881 MSOT Using Cetuximab-800CW for Detection of Cervical Lymph Node Metastases https://ClinicalTrials.gov/show/NCT03923881 Recruiting University Medical Center Groningen 2020-09-30
NCT03875118 Effects of Mouth-opening Training on the Maximum Interincisal Opening https://ClinicalTrials.gov/show/NCT03875118 Completed National Taipei University of Nursing and Health Sciences 2014-03-31
NCT03858712 EHR-embedded OCDT in Breast or GI Cancer https://ClinicalTrials.gov/show/NCT03858712 Recruiting Dana-Farber Cancer Institute 2021-03-31
NCT03853655 Adjuvant Radiotherapy in Early Stage Oral Cancers https://ClinicalTrials.gov/show/NCT03853655 Recruiting Tata Memorial Hospital 2022-08-01
NCT03843515 Neoadjuvant Nivolumab for Oral Cancer Combined With FDG and Anti-PD-L1 PET/CT Imaging for Response Prediction https://ClinicalTrials.gov/show/NCT03843515 Recruiting VU University Medical Center 2021-04-30
NCT01269190 Wide-Field and High Resolution In Vivo Imaging in Visualizing Lesions in Patients With Oral Neoplasia Undergoing Surgery https://ClinicalTrials.gov/show/NCT01269190 Recruiting M.D. Anderson Cancer Center 2020-12-31
NCT03749460 Nivolumab and Ipilimumab and Stereotactic Body Radiation Therapy in Treating Patients With Salivary Gland Cancers https://ClinicalTrials.gov/show/NCT03749460 Recruiting University of Washington 2022-12-22
NCT03737734 Alpha Radiation Emitters Device for the Treatment of Cutaneous, Mucosal or Superficial Soft Tissue Neoplasia (DaRT) https://ClinicalTrials.gov/show/NCT03737734 Recruiting Alpha Tau Medical LTD. 2020-12-31
NCT03685409 Cancer Chemoprevention by Metformin Hydrochloride in Oral Potentially Malignant Lesions https://ClinicalTrials.gov/show/NCT03685409 Recruiting Cairo University 2019-09-30
NCT03684707 Cancer Chemoprevention by Metformin Hydrochloride Compared to Placebo in Oral Potentially Malignant Lesions https://ClinicalTrials.gov/show/NCT03684707 Recruiting Ain Shams University 2019-06-15
NCT03653039 Comparison Between a Standard Tube and the Ultra-thin Tritube for Intubation of the Trachea and for Maintaining Access to the Trachea After Anaesthesia, in Patients With an Expected Difficult Direct Laryngoscopy https://ClinicalTrials.gov/show/NCT03653039 Recruiting Rigshospitalet, Denmark 2019-03-31
NCT03638622 Low-cost Enabling Technology for Image-guided Photodynamic Therapy (PDT) of Oral Cancer Cancer. https://ClinicalTrials.gov/show/NCT03638622 Completed Massachusetts General Hospital 2019-08-31
NCT03604939 Improving Access to Control of Diseases for Women https://ClinicalTrials.gov/show/NCT03604939 Completed International Agency for Research on Cancer 2018-07-01
NCT03602079 Study of A166 in Patients With Relapsed/Refractory Cancers Expressing HER2 Antigen or Having Amplified HER2 Gene https://ClinicalTrials.gov/show/NCT03602079 Recruiting Klus Pharma Inc. 2020-10-31
NCT03575598 Sitravatinib (MGCD516) and Nivolumab in Oral Cavity Cancer Window Opportunity Study https://ClinicalTrials.gov/show/NCT03575598 Recruiting University Health Network, Toronto 2020-08-30
NCT03545100 Rehabilitation Outcomes of Shoulder Function in Oral Cancer Survivors Cancer Survivors https://ClinicalTrials.gov/show/NCT03545100 Recruiting Chang Gung Memorial Hospital 2020-02-29
NCT01254617 Lenalidomide and Cetuximab in Treating Patients With Advanced Colorectal Cancer or Head and Neck Cancer https://ClinicalTrials.gov/show/NCT01254617 Completed National Cancer Institute (NCI) 2014-01-29
NCT01195922 Rapamycin Therapy in Head and Neck Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT01195922 Completed National Institutes of Health Clinical Center (CC) 2015-06-30
NCT01192204 Clinical Evaluation of Bioadhesive Gels for Oral Cancer Chemoprevention https://ClinicalTrials.gov/show/NCT01192204 Completed Ohio State University 2014-02-28
NCT01116843 Study to Assess Biomarkers in Patients With Resectable Oral Cavity Cancer Randomized to Receive Preoperative Treatment https://ClinicalTrials.gov/show/NCT01116843 Completed University Health Network, Toronto 2012-02-29
NCT01108042 TPF-Induction Chemotherapy of Oropharyngeal and Cavity of the Mouth Cancer https://ClinicalTrials.gov/show/NCT01108042 Completed University of Jena 2016-01-31
NCT00953849 Vitamin D Plus Celecoxib Therapy to Stimulate Intratumoral Immune Reactivity https://ClinicalTrials.gov/show/NCT00953849 Completed VA Office of Research and Development 2015-12-31
NCT00933387 A Study of Neoadjuvant Bio-C/T Followed by Concurrent Bio-R/T in High-risk Locally Advanced Oral Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT00933387 Completed National Health Research Institutes, Taiwan 2011-07-31
NCT00847717 Trial of IIb Preserving Neck Dissection https://ClinicalTrials.gov/show/NCT00847717 Completed Banaras Hindu University 2009-08-31
NCT02581137 Metformin Hydrochloride in Preventing Oral Cancer in Patients With an Oral Premalignant Lesion https://ClinicalTrials.gov/show/NCT02581137 Active, not recruiting National Cancer Institute (NCI) 2017-10-12
NCT03529422 Durvalumab With Radiotherapy for Adjuvant Treatment of Intermediate Risk SCCHN https://ClinicalTrials.gov/show/NCT03529422 Recruiting UNC Lineberger Comprehensive Cancer Center 2021-02-15
NCT04393506 Inductive Camrelizumab and Apatinib for Patients With Locally Advanced and Resectable Oral Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT04393506 Recruiting Shanghai Jiao Tong University School of Medicine 2020-12-31
NCT00721799 F-18 Fluorothymidine PET Imaging for Early Evaluation of Response to Therapy in Head & Neck Cancer Patients https://ClinicalTrials.gov/show/NCT00721799 Completed University of Iowa 2014-12-31
NCT00542373 Widefield Fluorescence and Reflectance Imaging Systems and Oral Tissue Samples in Monitoring Participants at Risk for Developing Oral Cancer https://ClinicalTrials.gov/show/NCT00542373 Active, not recruiting M.D. Anderson Cancer Center 2020-08-31
NCT00507182 Spectroscopy for Diagnostic Assessment of Oral Mucosal Lesions https://ClinicalTrials.gov/show/NCT00507182 Completed M.D. Anderson Cancer Center 2018-01-12
NCT00402779 Erlotinib Prevention of Oral Cancer (EPOC) https://ClinicalTrials.gov/show/NCT00402779 Completed M.D. Anderson Cancer Center 2018-06-04
NCT00359645 Randomized Trial to Assess the Impact of a Screening Program on Upper Aerodigestive Tract Cancer Mortality in a High Risk Population https://ClinicalTrials.gov/show/NCT00359645 Completed Gustave Roussy, Cancer Campus, Grand Paris 2015-12-18
NCT00330382 Bowman-Birk Inhibitor Concentrate in Preventing Cancer in Patients With Oral Leukoplakia https://ClinicalTrials.gov/show/NCT00330382 Completed National Cancer Institute (NCI) 2010-07-31
NCT00162708 Very Intense Radiotherapy-Chemotherapy Regimen in Advanced HNSCC https://ClinicalTrials.gov/show/NCT00162708 Completed Gustave Roussy, Cancer Campus, Grand Paris NA
NCT00158678 IMRT Plus Cisplatin Versus Conventional Radiotherapy Plus Cisplatin in Stage III-IV HNSCC https://ClinicalTrials.gov/show/NCT00158678 Completed Groupe Oncologie Radiotherapie Tete et Cou 2020-03-22
NCT00158652 Accelerated Radiotherapy and Concomitant Chemo-radiotherapy in HNSCC https://ClinicalTrials.gov/show/NCT00158652 Completed Groupe Oncologie Radiotherapie Tete et Cou 2011-03-31
NCT00064103 Gene Therapy in Preventing Cancer in Patients With Premalignant Carcinoma of the Oral Cavity or Pharynx https://ClinicalTrials.gov/show/NCT00064103 Completed National Cancer Institute (NCI) 2007-08-31
NCT00028405 Photodynamic Therapy System for Patients With Refractory/Unresponsive Solid Tumors https://ClinicalTrials.gov/show/NCT00028405 Completed Light Sciences LLC NA
NCT00750503 Workplace Tobacco Cessation And Oral Cancer Screening Study https://ClinicalTrials.gov/show/NCT00750503 Completed Tata Memorial Hospital 2008-06-30

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03304132 The Oral Microbiome and Upper Aerodigestive Squamous Cell Cancer https://ClinicalTrials.gov/show/NCT03304132 Completed NYU Langone Health 2010-12-01
NCT03206242 Rehabilitation Outcomes in Head and Neck Survivors https://ClinicalTrials.gov/show/NCT03206242 Completed Chang Gung Memorial Hospital 2016-06-30
NCT02663583 Intensity-Modulated Proton Therapy (IMPT) or TransOral Robotic Surgery (TORS) for the Treatment of Low-Risk Oropharynx Squamous Cell https://ClinicalTrials.gov/show/NCT02663583 Recruiting M.D. Anderson Cancer Center 2020-12-31
NCT02648789 Validation of DNA Methylation Biomarkers for Oral Cancer Detection https://ClinicalTrials.gov/show/NCT02648789 Completed Taipei Veterans General Hospital, Taiwan 2017-05-31
NCT00341497 Biomarkers for Oral Cancer https://ClinicalTrials.gov/show/NCT00341497 Completed National Institutes of Health Clinical Center (CC) NA
NCT02507141 Reflectance Confocal Microscopy of Oral Cancers in Vivo: a Preliminary Trial Comparing Intra-oral Imaging With Pathology https://ClinicalTrials.gov/show/NCT02507141 Recruiting Memorial Sloan Kettering Cancer Center 2020-07-31
NCT02323672 Salivary and Serum Levels of Chemerin and MMP-9 in Oral Premalignant and Malignant Lesions https://ClinicalTrials.gov/show/NCT02323672 Completed Cairo University 2014-09-30
NCT02048631 Analysis Of Sensory Recovery Of Donor Size And Quality Life In Oral Cancer Patients https://ClinicalTrials.gov/show/NCT02048631 Completed Kaohsiung Medical University Chung-Ho Memorial Hospital 2014-02-28
NCT01945697 Validation of DNA Methylation Biomarkers for Oral Cancer Detection https://ClinicalTrials.gov/show/NCT01945697 Completed National Taiwan University Hospital 2014-09-30
NCT01817140 Assessment of Mandibular Bone Invasion With MRI Using SWIFT https://ClinicalTrials.gov/show/NCT01817140 Completed University of Minnesota 2017-09-01
NCT01531881 Autofluorescence Detection of Oral Malignancies and Database and Biospecimen Collection to Identify Biomarkers of Head and Neck Tumor Progression https://ClinicalTrials.gov/show/NCT01531881 Active, not recruiting Roswell Park Cancer Institute 2014-01-31
NCT04267419 Malondialdehyde and Nitrous Oxide as Salivary Biomarkers for Different Oral Lesions https://ClinicalTrials.gov/show/NCT04267419 Completed Beni-Suef University 2019-12-15
NCT04163029 Oral Care Study of Postoperative Infections https://ClinicalTrials.gov/show/NCT04163029 Recruiting University of Liege 2021-12-01
NCT04041141 Oral Stent Device for Radiation Treatments of Oral Cancers https://ClinicalTrials.gov/show/NCT04041141 Recruiting Indiana University 2020-09-30
NCT03905005 Jaw Reconstruction With Printed Titanium and Free Tissue Transfer https://ClinicalTrials.gov/show/NCT03905005 Recruiting University of South Wales 2020-09-30
NCT03877159 Analysis of the Variation in Caspase-8 Availability and Cleavage in Oral Squamous Cell Carcinoma https://ClinicalTrials.gov/show/NCT03877159 Recruiting Guy’s and St Thomas’ NHS Foundation Trust 2020-01-30
NCT03862066 Memory Phenotype in Oral Cancer https://ClinicalTrials.gov/show/NCT03862066 Recruiting Medical University of South Carolina 2020-12-01
NCT03776578 Oral Cancer With Wide Excision and Free Flap Reconstruction https://ClinicalTrials.gov/show/NCT03776578 Recruiting National Taiwan University Hospital 2021-06-30
NCT03686020 Sensitivity and Specificity of Serum and Salivary CYFRA21-1 in the Detection of Malignant Transformation in Oral Potentially Malignant Mucosal Lesions (Diagnostic Accuracy Study) https://ClinicalTrials.gov/show/NCT03686020 Recruiting Cairo University 2019-10-31
NCT03555721 CytID Analysis of Oral Lesions https://ClinicalTrials.gov/show/NCT03555721 Recruiting The University of Texas Health Science Center, Houston 2019-11-01
NCT03529604 Salivary Ap4A, SCCA, TROP2 in Oral Cancer Patients https://ClinicalTrials.gov/show/NCT03529604 Active, not recruiting University of Zagreb 2020-04-01
NCT01104714 Pharmacogenetic Response to Chemotherapy Induction for ORL Cancers https://ClinicalTrials.gov/show/NCT01104714 Completed Centre Hospitalier Universitaire de Nīmes 2014-07-31
NCT01084733 Nicotine Levels With Response Rates to Radiation Alone or With Chemo In Head & Neck Cancer https://ClinicalTrials.gov/show/NCT01084733 Active, not recruiting University of Kentucky 2021-02-28
NCT01039272 Epstein-Barr Detection in Oral Cancer https://ClinicalTrials.gov/show/NCT01039272 Completed UPECLIN HC FM Botucatu Unesp 2008-04-30
NCT01862809 Cigarette Smoking and Oral Microbiota https://ClinicalTrials.gov/show/NCT01862809 Completed National Institutes of Health Clinical Center (CC) 2014-12-05
NCT00867464 Extended Follow-Up of Young Women in Costa Rica Who Received Vaccination Against Human Papillomavirus Types 16 and 18 and Unvaccinated Controls https://ClinicalTrials.gov/show/NCT00867464 Active, not recruiting National Institutes of Health Clinical Center (CC) NA
NCT00526851 Oral Cancer Screening Among Nursing Home Dentists in Ohio https://ClinicalTrials.gov/show/NCT00526851 Completed Case Comprehensive Cancer Center 2008-01-31
NCT00502580 Evaluation of a Multispectral Vision Enhancement System for Assessment of Oral Mucosal Lesions https://ClinicalTrials.gov/show/NCT00502580 Completed M.D. Anderson Cancer Center 2008-03-31
NCT00502125 In Vivo Confocal Imaging of Oral Mucosa https://ClinicalTrials.gov/show/NCT00502125 Completed M.D. Anderson Cancer Center 2009-09-30
NCT00439205 Oral Margin Spectroscopy Detection Using Optical Spectroscopy https://ClinicalTrials.gov/show/NCT00439205 Completed M.D. Anderson Cancer Center 2017-10-10
NCT00412490 Smoking Status and Body Image in Oral Cancer Patients https://ClinicalTrials.gov/show/NCT00412490 Completed M.D. Anderson Cancer Center 2014-12-31
NCT00364715 Study the Expression of Annexin A1 and Its Potential Usage as a Prognostic Marker in Oral Cancer https://ClinicalTrials.gov/show/NCT00364715 Completed National Taiwan University Hospital NA
NCT00200837 Ethnopharmacological Studies in Oral Medicine https://ClinicalTrials.gov/show/NCT00200837 Completed National Center for Complementary and Integrative Health (NCCIH) NA
NCT00186433 A Longitudinal Study of Plasma EBV DNA in Nasopharyngeal Carcinoma From Both Endemic and Non-Endemic Patient Populations https://ClinicalTrials.gov/show/NCT00186433 Completed Stanford University 2013-06-30
NCT00011492 Patient Evaluation for Head and Neck Surgery Branch Studies https://ClinicalTrials.gov/show/NCT00011492 Recruiting National Institutes of Health Clinical Center (CC) NA

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT03202810 Innovative Approach to Triage Oral Precancer https://ClinicalTrials.gov/show/NCT03202810 Recruiting British Columbia Cancer Agency 2021-11-14
NCT02012699 Integrated Cancer Repository for Cancer Research https://ClinicalTrials.gov/show/NCT02012699 Recruiting University of Nebraska 2099-12-31
NCT04081038 Dental Hygienists and Dentists as Providers of Oral Mucosa Screening and Brush Biopsies https://ClinicalTrials.gov/show/NCT04081038 Recruiting Dalarna County Council, Sweden 2020-12-31